Telomerase.org

Kanzius Machine and Cancer

2011-03-06T21:15:00.000-05:00

Telomerase found to be the core pathway of aging.

2011-02-15T02:03:00.000-05:00

Telomerase found to be the core pathway of aging.

Decrepit Mice's Age Partially Reversed with Telomerase!

2010-11-28T22:35:00.000-05:00

Business Week Article

Exercise: Does it help or hurt telomere length and aging?

2009-10-15T20:49:00.000-04:00

There seems to be conflicting evidence on the effects of exercise on telomere length. For some people, telomeres appear to shorten dramatically, presumably due to the stress on cells to repair damage caused by exercise. For other people, however, telomeres actually seem to get longer with exercise. The medical community say that exercise is good, and this message is constant and clear. But if some people age prematurely as a result of exercise, doesn't it make sense to know why? If we can identify those people whom it will hurt, we can tell them not to exercise.

Scand J Med Sci Sports. 2009 Sep 17

Mood disorders shorten your life

2009-10-15T06:29:00.000-04:00

People with mood disorders (depression, bipolar) in this study were found to have telomeres shorter by the equivalent of 10 years of aging.

This should prompt major medical attention and intervention.

Reasons to eat blueberries, plums, and other antioxidant sources

2009-10-10T19:38:00.000-04:00

It has been shown that high free radical levels accelerate telomere shortening. Hum Mol Genet 1997 Jun;6(6):905-908.

So, vitamin D, antioxidants, and reduced stress are what we are looking for to keep telomeres long.

Nobel Prize -- Congratulations to those who discovered telomerase!

2009-10-07T01:52:00.000-04:00

Took long enough to get there, but the Nobel Prize was bound to happen.

Telomerase has major implications for healthy aging, diseases, and cancer. This blog will continue to profile interesting developments with respect to telomeres and telomerase.

For now, remember that lowering perceived stress and taking an adequate vitamin D supplement are two ways to protect telomeres.

An article on older women, stress, and telomere loss.

More education=lower stress, and likely longer telomeres as well. (You are buying more than knowledge when you go to college!)

Webpage Excerpt: Vitamin D=longer telomeres, slower aging

2009-09-25T01:03:00.000-04:00

As a measure of systemic telomere length, generally, peripheral blood leukocyte telomere length is preferred. Systemic telomere length has been proposed as a marker of biological aging. A subject's systemic telomere length is predominantly genetically determined, but has several other known determinants: age (shorter telomeres in older people), paternal age at birth (longer telomeres in subjects with older fathers at their birth) and sex (shorter telomeres in men, probably due to a faster telomere attrition). Evidence suggests that elevated levels of oxidative stress and inflammation further increase the telomere attrition rate.[14]

Vitamin D may have an effect on peripheral blood leukocyte telomere length. Richards and coworkers examined whether vitamin D concentrations would slow the rate of shortening of leukocyte telomeres. The authors stated that vitamin D is a potent inhibitor of the proinflammatory response and slows the turnover of leukocytes. Leukocyte telomere length (LTL) predicts the development of aging-related disease, and length of these telomeres decreases with each cell division and with increased inflammation. Researchers measured serum vitamin D concentrations in 2160 women aged 18–79 years (mean age: 49.4) from a large population-based cohort of twins. This study divided the group into thirds based on vitamin D levels, and found that increased age was significantly associated with shorter LTL (r = -0.40, P < 0.0001). Higher serum vitamin D concentrations were significantly associated with longer LTL (r = 0.07, P = 0.0010), and this finding persisted even after adjustment for age (r = 0.09, P < 0.0001) and other variables that independently could affect LTL (age, season of vitamin D measurement, menopausal status, use of hormone replacement therapy, and physical activity). The difference in LTL between the highest and lowest tertiles of vitamin D was highly significant (P = 0.0009), and the authors stated that this was equivalent to 5.0 years of aging. The authors concluded that higher vitamin D levels, (easily modifiable through nutritional supplementation), were associated with longer LTL, which underscores the potentially beneficial effects of vitamin D on aging and age-related diseases.

http://www.archhill.co.nz/component/option,com_awiki/article,Telomere/lang,en/view,mediawiki/

First Doctor Offering Telomerase Activation w/TA65

2009-09-20T20:44:00.000-04:00

Science has cracked the code of aging. You’ll soon be able to use this science to enjoy the power of youth no matter what your age with a simple, completely safe, natural treatment - in a single tablet.

This cutting-edge anti-aging supplement is called TA-65.

TelomeraseActivation.org

Prostate Cancer: Moderately Linked to Telomerase

2009-09-20T20:18:00.000-04:00

DKC1 overexpression associated with prostate cancer progression

Article abstract

Telomerase and Hypertension

2009-09-20T20:13:00.000-04:00

Mice deficient in telomerase activity develop hypertension because of an excess of endothelin production.

Click here for abstract

Telomeres, Telomerase, and Artery Aging

2009-09-20T19:48:00.000-04:00

One new marker of increased pulse pressure and arterial ageing is telomere length, as regulated by telomerase enzymatic activity.

Click here for Pubmed Article Abstract

Keeping in touch

2009-09-20T08:55:00.000-04:00

I plan to feature an interesting article everyday about telomerase and its impacts on cancer, aging, stem cells, and various new treatments. Please feel free to add a feed from this site to keep up.

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Telomerase Videos

2009-09-20T04:49:00.000-04:00

Professor Elissa Epel on Telomerase, Stress, and Aging

Telomerase Innovator Geron on Stem Cells